Tumour cells in a mouse’s brainBruno Cisterna/Nikon Small World
A snapshot of a delicate web of tumour cells inside a mouse’s brain has clinched the top prize in this year’s Nikon Small World photography competition, which celebrates microscopy.
Tightly packed, upright strands of a protein known as actin border each cell, which contain green jumbles of tiny tubes, called microtubules, that surround a violet nucleus.

Bruno Cisterna Irrazabal at Augusta University in Georgia, who took the photo, is exploring whether the breakdown of the structures around nuclei could influence the development of neurodegenerative conditions, such as Alzheimer’s disease.
“One of the main problems with neurodegenerative diseases is that we don’t fully understand what causes them,” he said in a statement. “To develop effective treatments, we need to figure out the basics first.”
Clumps of slime moulds within nets of thick threadsHenri Koskinen/Nikon Small World
Maroon-coloured fruiting bodies of slime moulds, belonging to the species Cribraria cancellata, glisten in another entry, taken by Henri Koskinen at the University of Helsinki in Finland. A dainty net of thick threads, known as a peridium, encloses a clump of spores.
A cross-section of European beachgrassGerhard Vlcek/Nikon Small World
Photographer Gerhard Vlcek captured this vibrant cross-section of European beachgrass (Ammophila arenaria), taken from the Austrian city of Maria Enzersdorf. The turquoise tubes adjacent to the plant’s orange tissue are vascular bundles made up of xylem and phloem, which carry water and food.
Miniature scales from the wings of a Ulysses butterflyDaniel Knop/Nikon Small World
The azure flecks on the end of this syringe needle are miniature scales from the wings of a Ulysses butterfly (Papilio ulysses). Each scale can be as small as 30 micrometres in length. The astonishing shot was taken by photographer Daniel Knop in Germany.
The eight eyes of a green crab spiderPaweł Błachowicz/Nikon Small World
Paweł Błachowicz in Poland got up close and personal with a green crab spider (Diaea dorsata) to capture this intimate photo of its eight eyes. This species is no more than 6 millimetres across.
Translucent water fleas at different stages of reproductionMarek Miś/Nikon Small World
This wonderfully neon image of two translucent water fleas (Daphnia sp.) was taken by Marek Miś in Poland. The one on the left is filled with embryos, while its companion is replete with eggs.
A cross-section of a common brackenDavidMaitland/Nikon Small World
Vascular bundles form an expressive smile in this cross-section of a common bracken (Pteridium aquilinum) stem, taken by David Maitland in the UK.

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